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| 1438 |
| | The French clergy pass a resolution at Bourges, limiting the power of the papacy within France, which is adopted by the king as a 'pragmatic sanction' | |
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| 1516 |
| | Erasmus publishes an influential edition of the New Testament in its original Greek | |
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| 1517 |
| | The local sale of indulgences by Johann Tetzel outrages a friar teaching in Wittenberg, Martin Luther | |
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| 1517 |
| | Martin Luther nails his 95 Theses to the door of the castle church in Wittenberg | |
| | Woodcut portrait of Martin Luther National Archives, Kew
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| 1518 |
| | Philipp Melanchthon joins the Wittenberg university to teach Greek and inspires Luther to translate the New Testament | |
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| c. 1520 |
| | Europe's new printing presses make possible the first pamphlet war, spreading instant arguments for and against the Reformation | |
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| 1520 |
| | Luther's writings are burnt in Rome by order of the pope | |
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| 1521 |
| | Pope Leo X excommunicates Martin Luther after he has refused to recant | |
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| 1521 |
| | Luther travels to the German city of Worms to present his case to an imperial diet | |
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| 1521 |
| | Luther bears witness to a Protestant conscience, stating at Worms: 'Here I stand, I can not do otherwise.' | |
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